Cardioprotection From Ischemia/Reperfusion Injury
نویسندگان
چکیده
منابع مشابه
Preconditioning and postconditioning: innate cardioprotection from ischemia-reperfusion injury.
Reperfusion is the definitive treatment to salvage ischemic myocardium from infarction. A primary determinant of infarct size is the duration of ischemia. In myocardium that has not been irreversibly injured by ischemia, reperfusion induces additional injury in the area at risk. The heart has potent innate cardioprotective mechanisms against ischemia-reperfusion that reduce infarct size and oth...
متن کاملSpotlight on cardioprotection against ischemia-reperfusion injury.
Worldwide, coronary heart disease (CHD) causes approximately one-third of all deaths in men and one-quarter of all deaths in women and represents a significant threat to public health. The global burden of CHD in terms of disability-adjusted life years (DALY) or " healthy years of life lost " is projected to increase from around 47 million DALY globally in 1990 to 82 million in 2020 [1]. Myocar...
متن کاملInvited Review HIGHLIGHTED TOPIC Perspectives in Innate and Acquired Cardioprotection Preconditioning and postconditioning: innate cardioprotection from ischemia-reperfusion injury
Vinten-Johansen J, Zhao Z, Jiang R, Zatta AJ, Dobson GP. Preconditioning and postconditioning: innate cardioprotection from ischemia-reperfusion injury. J Appl Physiol 103: 1441–1448, 2007; doi:10.1152/japplphysiol.00642.2007.— Reperfusion is the definitive treatment to salvage ischemic myocardium from infarction. A primary determinant of infarct size is the duration of ischemia. In myocardium ...
متن کاملThe Role of Exercise Preconditioning in Cardioprotection against Ischemia Reperfusion Injury
Cardiovascular diseases are still the main cause of mortality around the world. Therefore, it is essential to develop practical means to reduce their burden. A wealth of evidence supports the role of physical exercise in attenuating many of the risk factors of cardiovascular diseases. Moreover, endurance training warrants protection against myocardial infarction. Exercise, even if performed ...
متن کاملResveratrol Provides Cardioprotection after Ischemia/reperfusion Injury via Modulation of Antioxidant Enzyme Activities
In this study, we investigated the cardioprotective effects of resveratrol. Rats were intraperitoneally administered with resveratrol (25 mg/kg bw) or vehicle (ethanol 10%) for 7 days and their heart subjected to ischemia/reperfusion injury. Isolated hearts were langendorff perfused, left ventricular functions as heart rate and developed pressure, as well as, heart antioxidant status were deter...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Circulation Journal
سال: 2012
ISSN: 1346-9843,1347-4820
DOI: 10.1253/circj.cj-12-0132